Improved Preparation Method for Mixed Functional Phase Silica Packing Materials for Liquid Chromatography.

Noncrystalline L-Phenylalanine-Silica Hybrid Composite Materials for High Selective Reversed Phase Liquid Chromatography

Preparation and characterization of surfactin-modified silica stationary phase for reversed-phase and hydrophilic interaction liquid chromatography.

Surfactants are good candidates as selectors in mixed-mode reversed-phase liquid chromatography (RPLC)/hydrophilic interaction liquid chromatography (HILIC) because they contain both a hydrophobic and a hydrophilic moiety. Surfactin, a cyclic heptapeptide, is an efficient biosurfactant produced by Bacillus subtilis that comprises seven amino acids and a β-hydroxyl fatty acid. A surfactin-modifi...

Silica based click amino stationary phase for ion chromatography and hydrophilic interaction liquid chromatography.

A silica based amino stationary phase was prepared by immobilization of propargylamine on azide-silica via click chemistry. This readily prepared click amino stationary phase demonstrated good selectivity in separation of common inorganic anions under ion chromatography (IC) mode, and the triazole ring in combination with free amino group was observed to play a major role for separation of the ...

Poly(L-lactic acid)-modified silica stationary phase for reversed-phase and hydrophilic interaction liquid chromatography.

Poly(L-lactic acid) is a linear aliphatic thermoplastic polyester that can be produced from renewable resources. A poly(L-lactic acid)-modified silica stationary phase was newly prepared by amide bond reaction between amino groups on aminopropyl silica and carboxylic acid groups at the end of the poly(L-lactic acid) chain. The poly(L-lactic acid)-silica column was characterized in reversed-phas...

J - Cyclodextrin / Diol Phase Silica Analysis of Drug Enantiomers in Liquid Chromatography Materials for Serum by Direct Injection

13-Cyclodextrin (CD)/diol phase silica materials have been designed for direct serum injection assays of drug enantiomers. The mixed functional phase (MFP) materials having /3-CD and diol phases were synthesized in four steps: introduction of a 3-chloropropyl phase, introduction of a /3-CD phase by ether linkage, introduction of a 3glycidoxypropyl phase and hydrolysis of the oxirange ring to a ...